http://www.liquidelearning.com/2007/11/guis-that-work-with-how-learner

If you want to learn how to design a great user interface that takes account of your learners' strengths and weaknesses, you should check out this article by Andy Bryce, who blogs at Successful Software.
Andy explains how our brain copes with information input, and then applies this to how we intake information from a GUI.
For me this article isn't just useful for GUI designers, it's also relevant for instructional designers. It helps explain short-term memory, long-term retention, perception and cognition.
Anyway. Don't waste your reading time here - go read about GUI design and How Your Brain Works!
Keywords: e-learning, language language, web 2.0
